I am a bioinformatics scientist at Stanford Center for Biomedical Informatics Research. My research interests focus on translational bioinformatics, integrating genomic, genetic, phenotypic and clinical data to identify diagnostics biomarkers, disease mechanisms and therapeutical drugs.

I have been working on translational bioinformatics from three directions. First, I have been developing comprehensive databases for genomic, genetic and phenotypic data. An example of this was a work on annotating gene expression data published in Nature Methods (2007). Second, I have been developing tools to reason over genomic, genetic and phenotypic data. An example of this is a work on prioritizing disease SNPs using gene expression data published in Genome Biology (2008). Third, I have been identifying diagnostic biomarkers and validating them in clinical settings. An example of this is a work on the identification of four non-invasive protein biomarkers for solid-organ transplant rejection (pdf).

Dr. Chen received his undergradute degree in Chemical Physics from the University of Science and Technology of China in 1994, his M.S. degree in Protein Crystallography and Organic Chemistry from Shanghai Institute of Organic Chemistry of Chinese Academy of Science in 1997, and his Ph.D. degree with Prof. Zhiping Weng in bioinformatics from Boston University in 2003. After graduation, he worked as a Scientist at Accelrys (on the Discovery Studio team), a computational Biologist at Amgen (on the Antibody Discovery team), and a principal software engineer at Nichols Institute of Quest Diagnostics (on the development of novel diagnostic assays).

If you feel like knowing more, here are some photos with my wife and my daughter.